Actress Teri Garr, best known for her comedic roles_,_has died at age 79. She worked with several high profile directors including Mel Brooks in Young Frankenstein, Steven Spielberg in Close Encounters of the Third Kind, and Sydney Pollack in Tootsie.

She had suffered for years with Multiple Sclerosis after being diagnosed with the degenerative disease in 1999. Garr was “surrounded by family and friends” at the time of her death, publicist Heidi Schaeffer told The Hollywood Reporter.